- This facility is equipped with the following intsruments:
-
-
- Finnigan LCQ MS: This is a quadrupole ion trap
instrument. Three ionization sources are available:
electrospray (ESI), atmospheric pressure chemical ionization (APCI)
and nanospray. The effective mass range is 2000 Da for
singly charged species, but is much higher for multiply charged
species.
- Services available:
- Mass determination:
simple mass determination of a compound.
- MSn:
structural determination of a compound - up to 9 generations of
ions can be isolated and subjected to fragmentation.
- LC/MS:
currently this is available coupling the HPLC to the ESI source to
do MS and MSn of eluting compounds.
-
- Waters 2690 HPLC: This instrument is equipped with a
Waters 996 Photodiode Array Detector and a 5 tray, 24 sample/tray
auto-sampler. This instrument is to be used in tandem with the LCQ.
-
-
- Bruker Proflex MALDI-TOF MS: This matrix-assisted laser
desorption/ionization mass spectrometer can detect compounds
between 500 and about 100,000 Da.
- Services available:
- Mass determination:
simple mass determination of a compound.
- Protein
identification: Peptide fragments of an enzymatically
digested protein can be used to ID the protein.
-
- Finnigan GCQ GC-MS: This is an ion trap
instrument. Two ionization sources are available:
electron impact ionization (EI) and chemical ionization (CI).
It has a mass range up to 1000 Da. It is equipped with a 90
sample tray auto-sampler.
- Services available:
- Mass determination:
simple mass determination of a compound.
- MS/MS:
structural determination of a compound - ions can be isolated and
subjected to fragmentation.
-
